Reading Time: 2 minutesIntroduction to Sildenafil Sildenafil, widely recognized under the brand name Viagra, is a pivotal medication in the treatment of erectile dysfunction (ED), a condition affecting a significant number of American males. This article delves into the pharmacokinetics of sildenafil, providing a detailed understanding of how this drug is absorbed, distributed, metabolized, and eliminated in the body, which is crucial for its effective use. Absorption of Sildenafil Sildenafil is rapidly absorbed following oral administration, with peak plasma concentrations achieved within 30 to 120 minutes. The bioavailability of sildenafil is approximately 41%, which can be influenced by food intake. A high-fat meal … Continue reading →