Reading Time: 2 minutesIntroduction Male breast cancer, though comprising less than 1% of all breast cancer diagnoses in the United States, affects approximately 2,800 American men annually according to the American Cancer Society's 2023 Surveillance, Epidemiology, and End Results (SEER) data. Tamoxifen, a selective estrogen receptor modulator (SERM), remains a cornerstone of adjuvant endocrine therapy for hormone receptor-positive cases, mirroring its application in female patients. While efficacious in reducing recurrence risk by up to 50% in clinical trials like ATAC and NSABP B-14, emerging pharmacovigilance reports from the FDA's Adverse Event Reporting System (FAERS) highlight vestibular perturbations and balance deficits as underrecognized adverse … Continue reading
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