Reading Time: 2 minutesIntroduction Tamoxifen, a cornerstone in the pharmacological arsenal against breast cancer, has been extensively studied for its ability to inhibit the growth of cancer cells. This article delves into the experimental studies that have illuminated the mechanisms through which tamoxifen exerts its anti-proliferative effects, with a particular focus on its relevance to American males. Mechanism of Action Tamoxifen operates primarily as a selective estrogen receptor modulator (SERM). By competitively binding to estrogen receptors on cancer cells, tamoxifen blocks the proliferative effects of estrogen, which is crucial in hormone-sensitive cancers. Experimental studies have shown that tamoxifen induces apoptosis and cell cycle … Continue reading
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