Reading Time: 3 minutesIntroduction Jatenzo, an oral testosterone undecanoate capsule, represents a significant advancement in testosterone replacement therapy (TRT). Specifically designed to address hypogonadism in men, understanding the pharmacokinetics (PK) and pharmacodynamics (PD) of Jatenzo is crucial for optimizing its therapeutic efficacy and safety. This article delves into the absorption, distribution, metabolism, and excretion of Jatenzo in American males, offering a detailed perspective on its clinical application. Absorption of Jatenzo Jatenzo is formulated to enhance the oral bioavailability of testosterone, which is typically challenging due to its first-pass metabolism in the liver. The capsule utilizes a proprietary lipid-based technology that facilitates the absorption … Continue reading
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